闻捷 研究员
发布人:中科院微观磁共振重点实验室  发布时间:2020-05-20   动态浏览次数:1260

姓名:

闻捷 研究员

工作单位:

中国科学技术大学附属第一医院

中国科学院微观磁共振重点实验室

电话:

0551-62283486

E-mail:

jiewen(AT)ustc.edu.cn

 

2007年获得中国科学技术大学应用物理学学士学位,2012年获得中国科学技术大学结构生物学博士学位。20122014年在美国圣路易斯华盛顿大学医学院从事磁共振成像方法学的博士后研究,并且于20142016年荣获美国多发性硬化学会(NMSS)颁发的博士后研究员(Postdoctoral Fellow)资助。20162018年间在圣路易斯华盛顿大学医学院任讲师一职。2019年正式加入中国科学技术大学附属第一医院。主持完成了NMSS研究项目1项,参与了包括NIH-R01等项目4项。在PNAS等杂志发表SCI论文17篇,拥有一项美国发明专利授权。相关研究成果在国际医学磁共振学会(ISMRM)年会,美国神经学会年会(ANA)以及美国多发性硬化治疗与研究学会年会(ACTRIMS)等国际学术会议上作口头报告,并受邀为NeuroImage等多个SCI收录学术期刊审稿。

  

  

  • 学历:

20039月-20077月,中国科学技术大学, 应用物理学, 学士。

20079月-20127月,中国科学技术大学, 结构生物学, 博士。。


  • 主要工作经历:

20129月-20146,圣路易斯华盛顿大学,博士后。

20147月-20166,美国多发性硬化学会,博士后研究员。

20167月-201812,圣路易斯华盛顿大学,讲师。

20191至今,中国科学技术大学附属第一医院,研究员。


  • 目前主持的主要科研项目:

1

《基于蓝藻气囊的靶向磁共振成像技术》,“科大新医学”联合基金培育项目,项目负责人,2019.8 – 2021.7

 

  • 代表性研究论文 :

  1. Xiang, B., Wen, J., Lu, H.C., Schmidt, R.E., Yablonskiy, D.A., Cross, A.H., In vivo evolution of biopsy-proven inflammatory demyelination quantified by R2t* mapping. Ann Clin Transl Neurol. 2020. doi: 10.1002/acn3.51052.

  2. Xiang, B., J. Wen, A.H. Cross, and D.A. Yablonskiy, Single scan quantitative gradient recalled echo MRI for evaluation of tissue damage in lesions and normal appearing gray and white matter in multiple sclerosis. J Magn Reson Imaging, 2019. 49(2): p. 487-498.

  3. Astafiev, S.V., J. Wen, D.L. Brody, A.H. Cross, A.P. Anokhin, K.L. Zinn, M. Corbetta, and D.A. Yablonskiy, A Novel Gradient Echo Plural Contrast Imaging Method Detects Brain Tissue Abnormalities in Patients With TBI Without Evident Anatomical Changes on Clinical MRI: A Pilot Study. Mil Med, 2019. 184(Suppl 1): p. 218-227.

  4. Wen, J., M.S. Goyal, S.V. Astafiev, M.E. Raichle, and D.A. Yablonskiy, Genetically defined cellular correlates of the baseline brain MRI signal. Proc Natl Acad Sci U S A, 2018. 115(41): p. E9727-E9736.

  5. Wen, J., A.L. Sukstanskii, and D.A. Yablonskiy, Phase-sensitive B1 mapping: Effects of relaxation and RF spoiling. Magn Reson Med, 2018. 80(1): p. 101-111.

  6. Cai, B., S.M. Goddu, S. Yaddanapudi, D. Caruthers, J. Wen, C. Noel, S. Mutic, and B. Sun, Normalize the response of EPID in pursuit of linear accelerator dosimetry standardization. J Appl Clin Med Phys, 2018. 19(1): p. 73-85.

  7. Adusumilli, G., K. Trinkaus, P. Sun, S. Lancia, J.D. Viox, J. Wen, R.T. Naismith, and A.H. Cross, Intensity ratio to improve black hole assessment in multiple sclerosis. Mult Scler Relat Disord, 2018. 19: p. 140-147.

  8. Wen, J., D.A. Yablonskiy, A. Salter, and A.H. Cross, Limbic system damage in MS: MRI assessment and correlations with clinical testing. PLoS One, 2017. 12(11): p. e0187915.

  9. Sukstanskii, A.L., J. Wen, A.H. Cross, and D.A. Yablonskiy, Simultaneous multi-angular relaxometry of tissue with MRI (SMART MRI): Theoretical background and proof of concept. Magn Reson Med, 2017. 77(3): p. 1296-1306.

  10. Zhao, Y., M.E. Raichle, J. Wen, T.L. Benzinger, A.M. Fagan, J. Hassenstab, A.G. Vlassenko, J. Luo, N.J. Cairns, J.J. Christensen, J.C. Morris, and D.A. Yablonskiy, In vivo detection of microstructural correlates of brain pathology in preclinical and early Alzheimer Disease with magnetic resonance imaging. Neuroimage, 2017. 148: p. 296-304.

  11. Cai, B., H. Li, D. Yang, V. Rodriguez, A. Curcuru, Y. Wang, J. Wen, R. Kashani, S. Mutic, and O. Green, Performance of a multi leaf collimator system for MR-guided radiation therapy. Med Phys, 2017. 44(12): p. 6504-6514.

  12. Zhao, Y., J. Wen, A.H. Cross, and D.A. Yablonskiy, On the relationship between cellular and hemodynamic properties of the human brain cortex throughout adult lifespan. Neuroimage, 2016. 133: p. 417-429.

  13. Wen, J., D.A. Yablonskiy, J. Luo, S. Lancia, C. Hildebolt, and A.H. Cross, Detection and quantification of regional cortical gray matter damage in multiple sclerosis utilizing gradient echo MRI. Neuroimage Clin, 2015. 9: p. 164-75.

  14. Mamah, D., J. Wen, J. Luo, X. Ulrich, D.M. Barch, and D. Yablonskiy, Subcomponents of brain T2* relaxation in schizophrenia, bipolar disorder and siblings: A Gradient Echo Plural Contrast Imaging (GEPCI) study. Schizophr Res, 2015. 169(1-3): p. 36-45.

  15. Wen, J., A.H. Cross, and D.A. Yablonskiy, On the role of physiological fluctuations in quantitative gradient echo MRI: implications for GEPCI, QSM, and SWI. Magn Reson Med, 2015. 73(1): p. 195-203.

  16. Wen, J., Zhou, P., Wu, J., Efficient acquisition of high-resolution 4-D diagonal-suppressed methyl-methyl NOESY for large proteins. J Magn Reson, 2012. 218: p. 128-132.

  17. Wen, J., Wu, J., Zhou, P., Sparsely sampled high-resolution 4-D experiments for efficient backbone resonance assignment of disordered proteins. J Magn Reson, 2011. 209(1): p. 94-100.