史朝为 研究员
发布人:中科院微观磁共振重点实验室  发布时间:2020-05-20   动态浏览次数:4522



姓名:

史朝为

工作单位:

中国科大 生命科学与医学部

中国科学院微观磁共振重点实验室

电话:

0551-63603819

E-mail:

scwei(AT)ustc.edu.cn

 

史朝为,男,19889月生于安徽。中国科学技术大学特任研究员。2013年获中国科学技术大学理学博士学位。长期从事膜蛋白核磁共振研究,发展了一系列固体核磁共振方法,提高蛋白质核磁谱的信号强度和灵敏度,并运用于功能性淀粉样蛋白、离子通道和膜蛋白酶的结构及功能研究。迄今为止,共发表论文24篇,其中以第一/通讯作者论文10篇。


  • 学历:

200409月-200807月,中国科学技术大学,生物技术,学士。

200809月-201311月,中国科学技术大学,结构生物学,博士。


  • 主要工作经历:

201403月-201406,德国 马普 生物物理化学所,博士后。

201407月-201902,德国 莱布尼茨 分子药物所,博士后。

201903至今,中国科大生命科学与医学部,特任研究员。



  • 代表性研究论文 :

(1) Zhang Jin; Li Juan; Wang Yusong; Shi Chaowei*; NMR methods to detect fluoride binding and transport by membrane proteins, Methods in Enzymology, 2024,696:25-42


(2) Ling Shenglong; Meng Xianyu; Zhang Yuan; Xia Zhemin; Zhou Yingxin; Yang Fan; Shi Pan*; Shi Chaowei*; Tian Changlin*; Structural insights into asymmetric activation of the calcium-sensing receptor–Gq complex, Cell Research, 2024, 34(2): 169-172


(3) Li Hao; Zhang Jin; Wang Zilong; Shi Pan; Shi Chaowei*; Genetically encoded site-specific 19F unnatural amino acid incorporation in V. natriegens for in-cell NMR analysis, Protein expression and purification, 2024, 219:106461


(4) Zhang Jin; Song Dan; Florian Karl Schackert; Li Juan; Xiang Shengqi; Tian Changlin; Gong Weimin; Paolo Carloni; Mercedes Alfonso-Prieto; Shi Chaowei*; Fluoride permeation mechanism of the Fluc channel in liposomes revealed by solid-state NMR, Science Advances, 2023, 9(34): eadg9709

 

(5) Zhao Rui; Shi Pan; Cui Ji-bin; Shi Chaowei*; Wei Xiao-Xiong; Luo Jie; Xia Zhemin; Shi WeiWei; Zhou Yingxin; Tang Jiahui; Tian Changlin; Meininghaus Mark; Bierer Donald; Shi Jing*; Li Yiming*; Liu Lei* ; SingleShot SolidPhase Synthesis of FullLength H2 Relaxin Disulfide Surrogates, Angewandte Chemie International Edition, 2023, 62(6): e202216365

 

(6) Song Dan; Kuang Lisha; Yang Lin; Wang Lei; Li Hao; Li Xiu; Zhu Zhimin; Shi Chaowei*; Zhu Haining*; Gong Weimin*; Yin and yang regulation of stress granules by Caprin-1, Proceedings of the National Academy of Sciences, 2022, 119(44): e2207975119

 

(7) Li Longmei; Zhang Jin; Sun Wenjing; Gong Weimin; Tian Changlin; Shi Pan*; Shi Chaowei*; Allosteric conformational changes of G proteins upon its interaction with membrane and GPCR,

Chinese Chemical Letters, 2022, 33(2): 747-750

 

(8) Shi Wei-Wei#; Shi Chaowei#; Wang Tong-Yue; Li Yu-Lei; Zhou Yong-Kang; Zhang Xu-Han; Bierer Donald; Zheng Ji-Shen; Liu Lei ; Total Chemical Synthesis of Correctly Folded Disulfide-Rich Proteins Using a Removable O-Linked β- N-Acetylglucosamine Strategy, Journal of the American Chemical Society, 2022, 144(1): 349-357

 

(9) Wang Yongjin#; Zhou Yang#; Shi Chaowei#; Liu Jiacong; Lv Guohua; Huang Huisi; Li Shengrong; Duan Liping; Zheng Xinyi; Liu Yue; Zhou Haibo; Wang Yonghua; Li Zhengqiu; Ding Ke; Sun Pinghua; HuangYun; Lu Xiaoyun; Zhang Zhi-Min; A toxin-deformation dependent inhibition mechanism in the T7SS toxin-antitoxin system of Gram-positive bacteria, Nature Communications, 2022, 13(1): 6434

 

(10) Shi Chaowei*; Oester Carl; Bohg Claudia; Li Longmei; Lange Sascha; Chevelkov Veniamin; Lange Adam*; Structure and Dynamics of the Rhomboid Protease GlpG in Liposomes Studied by SolidState NMR, Journal of the American Chemical Society, 2019, 141(43): 17314-17321