史朝为 研究员
发布人:中科院微观磁共振重点实验室  发布时间:2020-05-20   动态浏览次数:1839



姓名:

史朝为

工作单位:

中国科大 生命科学与医学部

中国科学院微观磁共振重点实验室

电话:

0551-63603819

E-mail:

scwei(AT)ustc.edu.cn

 

史朝为,男,19889月生于安徽。中国科学技术大学特任研究员。2013年获中国科学技术大学理学博士学位。长期从事膜蛋白核磁共振研究,发展了一系列固体核磁共振方法,提高蛋白质核磁谱的信号强度和灵敏度,并运用于功能性淀粉样蛋白、离子通道和膜蛋白酶的结构及功能研究。迄今为止,共发表论文24篇,其中以第一/通讯作者论文10篇。



 

  • 学历:

200409月-200807月,中国科学技术大学,生物技术,学士。

200809月-201311月,中国科学技术大学,结构生物学,博士。


  • 主要工作经历:

201403月-201406,德国 马普 生物物理化学所,博士后。

201407月-201902,德国 莱布尼茨 分子药物所,博士后。

201903至今,中国科大生命科学与医学部,特任研究员。



  • 代表性研究论文 :(按年代倒序排列,粗体突出本人和期刊名)

  1. Chaowei Shi, Carl Öster, Claudia Bohg, Longmei Li, Sascha Lange, Veniamin Chevelkov, Adam Lange, Structure and Dynamics of the Rhomboid Protease GlpG in Liposomes Studied by Solid-State NMR. J Am Chem Soc 2019 141, 17314-17321

  2. Chaowei Shi, Yao He, Kitty Hendriks, Bert L. de Groot, Xiaoying Cai, Changlin Tian, Adam Lange, Han Sun, A single NaK channel conformation is not enough for non-selective ion conduction. Nature Communications 9, 717 (2018).

  3. Chaowei Shi, Pascal Fricke, Lin Lin, Veniamin Chevelkov, Melanie Wegstroth, Karin Giller, Stefen Becker, Martin Thanbichler, Adam Lange, Atomic-resolution structure of cytoskeletal bactofilin by solid-state NMR. Science advances 1, e1501087 (2015).

  4. Suresh Vasa, Lin Lin, Chaowei Shi, Birgit Habenstein, Dietmar Riedel, Juliane Kuhn, Martin Thanbichler, Adam Lange, beta-Helical architecture of cytoskeletal bactofilin filaments revealed by solid-state NMR. Proceedings of the National Academy of Sciences 112, E127-136 (2015).

  5. Juan Li, Chaowei Shi, Demeng Sun, Yao He, Chaohua Lai, Pei Lv, Ying Xiong, Longhua Zhang, Fangming Wu, Changlin Tian, The HAB1 PP2C is inhibited by ABA-dependent PYL10 interaction. Scientific reports 5, 10890 (2015).

  6. Chaowei Shi, Hannes K. Fasshuber, Veniamin Chevelkov, Shengqi Xiang, Birgit Habenstein, Suresh K. Vasa, Stefen Becker, Adam Lange, BSH-CP based 3D solid-state NMR experiments for protein resonance assignment. Journal of biomolecular NMR 59, 15-22 (2014).

  7. Juan Li, Chaowei Shi, Yuan Gao, Kaiqi Wu, Pan Shi, Chaohua Lai, Liu Chen, Fangming Wu, Changlin Tian, Structural studies of Mycobacterium tuberculosis Rv0899 reveal a monomeric membrane-anchoring protein with two separate domains. Journal of molecular biology 415, 382-392 (2012).

  8. Chaowei Shi, Fang Han, Ying Xiong, Changlin Tian, A gas chromatography-mass spectrometry method to monitor detergents removal from a membrane protein sample. Protein expression and purification 68, 221-225 (2009).

  9. Jinxiu Zhang, Xiaojie Yan, Chaowei Shi, Xue Yang, Yu Guo, Changlin Tian, Jiafu Long, Yuequan Shen, Structural basis of beta-catenin recognition by Tax-interacting protein-1. Journal of molecular biology 384, 255-263 (2008).

  10. Chaowei Shi, Wei Shao, Ying Xiong, Changlin Tian, A gas chromatographic method for quantification of detergents frequently used in membrane protein structural studies. Analytical biochemistry 383, 326-328 (2008).